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Pyrimethamine sustained release systems based on bioresorbable polyesters for chemoprophylaxis of rodent malaria

✍ Scribed by M. Tsakala; J. Gillard; M. Roland; F. Chabot; M. Vert


Book ID
119133678
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
894 KB
Volume
5
Category
Article
ISSN
0168-3659

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✍ Verónica Lassalle; María Luján Ferreira 📂 Article 📅 2010 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 281 KB 👁 1 views

## Abstract **BACKGROUND:** Drug delivery systems (DDS) were designed using insulin as model drug and poly (lactic–co‐glycolic) copolymers (PLGA) as polymeric matrix. The carriers were synthesized by direct self‐assembly of the insulin and the polyester under mild conditions. **RESULTS:** The kind