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Pyridoxal-mediated abzyme system for aldol and retro-aldol reactions

✍ Scribed by Fujie Tanaka; Motoko Oda; Ikuo Fujii

Book ID: 104259465
Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 269 KB
Volume: 39
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(98)00952-6

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✦ Synopsis

A pyridoxal-mediated abzyme system for aldol and retro-aldol reactions is demonstrated. Antibody lOH2 catalyzes the aldol and retro-aldol reactions of 4-acetamidobenzaldehyde and glycine to P-hydroxy cr.-amino acid, using pyridoxal S-phosphate as a cofactor.

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