Pyridine synthesis via 4-(3-oxoalkyl)isoxazoles
✍ Scribed by Stork, Gilbert; Ohashi, M.; Kamachi, H.; Kakisawa, H.
- Book ID
- 120445670
- Publisher
- American Chemical Society
- Year
- 1971
- Tongue
- English
- Weight
- 444 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
Trimethylsilyl enol ethers ( 1 ) reacted with l-ethoxycarbonylpyridinium chloride (2 ) at 4-position with high rezoselectivity to afford l-ethoxycarbonyl-4-( 2-oxoalkyl )-1,4\_dihydropyridines ( 2 ) in 42 -8'7% yields. When 2, 2, 2-trichloroethyl chloroformate was employed, yields of the correspond
## A bstract Isoxmole-fused 3-su(foiene 12 has been synthesized from the readily available starting material 7 in three steps. Heating compound 12 at 160-180 C generates odimethylene isoxmole bb which undergoes smooth cycloaddition reactions. The generation and synthetic applications of o-quinodim
In the title compound, C 17 H 15 FN 2 O, the exocyclic bond angles at the C atoms of the isoxazole ring bearing the pyridyl and 4fluorophenyl substituents are 129.66 (17) and 134.58 ( 16) , respectively. The structure was determined in a study of the molecular geometry of isoxazole derivatives with