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Pyrazolo[1′,5′:1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as selective human A1 adenosine receptor ligands

✍ Scribed by Maria Paola Giovannoni; Claudia Vergelli; Agostino Cilibrizzi; Letizia Crocetti; Claudio Biancalani; Alessia Graziano; Vittorio Dal Piaz; Maria Isabel Loza; Maria Isabel Cadavid; José Luis Díaz; Amadeu Gavaldà

Book ID: 108072933
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 444 KB
Volume: 18
Category: Article
ISSN: 0968-0896
DOI: 10.1016/j.bmc.2010.09.043

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## Abstract magnified image Pyrimido[2“,1”:5′,6′]pyrazolo[3′,4′:4,5]‐pyrimido[1,6‐__a__]benzoimidazoloe‐2,8(1__H__,7__H__)‐diones, and [1,2,4]‐triazino‐[3“,4”:5′,6′]pyrazolo[3′,4′:4,5]pyrimido[1,6‐__a__]benzimidazol‐8(7__H__)‐ones were synthesized in a good yields __via__ 1‐amino‐4‐methyl‐3,4‐dihy