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Pyrazolo[1,5-a]pyrimidines. Identification of the Privileged Structure and Combinatorial Synthesis of 3-(Hetero)arylpyrazolo[1,5-a]pyrimidine-6-carboxamides

✍ Scribed by Gregg, Brian T.; Tymoshenko, Dmytro O.; Razzano, Dana A.; Johnson, Matthew R.

Book ID: 111647110
Publisher: American Chemical Society
Year: 2007
Tongue: English
Weight: 212 KB
Volume: 9
Category: Article
ISSN: 1520-4766
DOI: 10.1021/cc0700039

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Eingegangen am 16. Juli 1986 New 3-(pyridin-6-yl) pyraolo [ 1,5-u]pyrimidines were synthesized from (pyridin-6-y1)malonodinitrile 58, ethyl (pyridin-6-y1)cyanoacetate 5b and (pyridin-6-y1)benzoylacetonitrile 5c. Compounds 58-c were obtained from the 4,4,4-trichlorobut-2-enenitriles 2 and 1-pheny1et