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Pyrazolo[1,5-a]pyrimidines. A combined multinuclear magnetic resonance (1H, 13C, 15N, 19F) and DFT approach to their structural assignment

✍ Scribed by Dionisia Sanz; Rosa M. Claramunt; Anil Saini; Vinod Kumar; Ranjana Aggarwal; Shiv P. Singh; Ibon Alkorta; José Elguero


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
166 KB
Volume
45
Category
Article
ISSN
0749-1581

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✦ Synopsis


Abstract

Multinuclear magnetic resonance spectroscopy together with GIAO‐DFT calculations allowed establishment of the structure of the products obtained by condensation of 3(5)‐amino‐4‐phenyl‐1__H__‐pyrazole and β‐dicarbonyl compounds bearing a trifluoromethyl group. They are 3‐phenyl‐5‐(R)‐7‐trifluoromethylpyrazolo[1,5‐a]pyrimidines. Copyright © 2007 John Wiley & Sons, Ltd.