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Pyrazolo[1,5- a ]pyrimidines: Estrogen Receptor Ligands Possessing Estrogen Receptor β Antagonist Activity.

✍ Scribed by Compton, Dennis R.; Sheng, Shubin; Carlson, Kathryn E.; Rebacz, Natalie A.; Lee, In Young; Katzenellenbogen, Benita S.; Katzenellenbogen, John A.

Book ID
126794977
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
24 KB
Volume
48
Category
Article
ISSN
0022-2623

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## Abstract Recent work elucidating the role that the estrogen receptor β (ERβ), a member of the nuclear receptor superfamily, plays in regulating various physiological functions has highlighted the potential of this receptor subtype as a therapeutic target for several pathologies. In fact, molecul