Pyrazinamide-Induced Anaphylaxis: Diagnosed by Skin Test and Successful Desensitization

✍ Scribed by Bavbek, Sevim; Yılmaz, İnsu; Aydın, Ömür; Ozdemir, Seçil Kepil

• Book ID: 119985467
• Publisher: S. Karger AG
• Year: 2012
• Tongue: English
• Weight: 172 KB
• Volume: 157
• Category: Article
• ISSN: 1018-2438
• DOI: 10.1159/000327537

✦ Synopsis

Pyrazinamide (PZA), an antituberculosis drug, may cause hypersensitivity reactions. Here, we report a case of anaphylaxis secondary to a PZA administration for tuberculosis pleuritis. To the best of our knowledge, this is the first reported case of strongly possible IgE-mediated, PZA-induced anaphylaxis proved by skin prick test and oral provocation/desensitization.