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Pyk2/CAKβ signaling: a novel Ca2+-dependent pathway leading to cardiac hypertrophy

✍ Scribed by Toshiyuki Takahashi


Book ID
116983480
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
123 KB
Volume
36
Category
Article
ISSN
0022-2828

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## Abstract Cellular mechanisms causing cardiac hypertrophy are currently under intense investigation. We report a novel finding in the TGFβ inducible early gene (TIEG) null mouse implicating TIEG1 in cardiac hypertrophy. The TIEG^−/−^ knock‐out mouse was studied. Male mice age 4–16 months were cha