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PW03-007 - NLRP3 genetic variants in Schnitzler’s syndrome

✍ Scribed by HD De Koning,J Schalkwijk,JW van der Meer,PL Zeeuwen…

Book ID
126376535
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
87 KB
Volume
11
Category
Article
ISSN
1546-0096

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✍ Gregory J. Lewis; Dunecan C.O. Massey; Hu Zhang; Francesca Bredin; Mark Tremelli 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 106 KB

Background: NLRP3 (formerly known as CIAS1 or NALP3) encodes a key component of the inflammasome and is a strong candidate gene for Crohn's disease (CD) susceptibility. A recent study reported significant and internally replicated association between CD and six single nucleotide polymorphisms (SNPs)