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Putative tumor suppressor YueF affects the functions of hepatitis B virus X protein in hepatoma cell apoptosis and p53 expression

✍ Scribed by Jing Huang; Kailang Wu; Jianlin Zhang; Wei Si; Ying Zhu; Jianguo Wu

Publisher
Springer Netherlands
Year
2007
Tongue
English
Weight
344 KB
Volume
30
Category
Article
ISSN
0141-5492

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## Abstract This study examines the differential activities between wild‐type Hepatitis B virus X protein (WtHBx) and a mutant HBx (MutHBx), which bears a hotspot mutation at nucleotides 1,762 and 1,764, resulting in a lysine to methionine change at codon 130 and a valine to isoleucine change at co