Purinergic regulation of acid/base trans
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Γkos Zsembery; Carlo SpirlΓ¬; Anna Granato; Nicholas F. LaRusso; Lajos Okolicsany
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Article
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1998
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John Wiley and Sons
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English
β 123 KB
Biliary epithelial cells (cholangiocytes) are responsible for rapid regulation of bile volume and alkalinity. Secretin and other hormones raising intracellular cyclic adenosine monophosphate (cAMP) concentrations promote biliary HCO3 secretion by stimulating apical Cl- channels and Cl-/HCO3- exchang