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Purinergic receptor modulation of BV-2 microglial cell activity: Potential involvement of p38 MAP kinase and CREB

✍ Scribed by Vielska M. Brautigam; Chuenchanok Frasier; Maria Nikodemova; Jyoti J. Watters


Book ID
113729632
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
259 KB
Volume
166
Category
Article
ISSN
0165-5728

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## Abstract By using pharmacological and molecular approaches, we previously showed that the G‐protein‐coupled, extracellular calcium (Ca)‐sensing receptor (CaR) regulates a large‐conductance (∼140 pS), Ca^2+^‐activated K^+^ channel [I~K(Ca)~; CAKC] in U87 astrocytoma cells. Here we show that eleva