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Purinergic actions on neurons that modulate nociception in the rostral ventromedial medulla

✍ Scribed by N.R. Selden; J.D. Carlson; J. Cetas; L.N. Close; M.M. Heinricher

Book ID
116788155
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
977 KB
Volume
146
Category
Article
ISSN
0306-4522

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Within the rostral ventromedial medulla (RVM), there are two classes of putative pain modulation neurons: ON cells and OFF cells, which respectively burst or pause prior to withdrawal reflexes elicited by noxious stimulation. Alpha-adrenergic agonists injected into the RVM produce changes in the lat