## Abstract The breakdown of the blood–brain barrier (BBB) has been considered to be a key step in the disease process of a number of neurological disorders such as cerebral ischemia and Alzheimer's disease. Many in vitro BBB models derived from animal tissues have been established to elucidate the
✦ LIBER ✦
Purine receptors and Ca2+signalling in the human blood–brain barrier endothelial cell line hCMEC/D3
✍ Scribed by Willem Bintig; Daniela Begandt; Barbara Schlingmann; Linda Gerhard; Maria Pangalos; Lutz Dreyer; Natalija Hohnjec; Pierre-Olivier Couraud; Ignacio A. Romero; Babette B. Weksler; Anaclet Ngezahayo
- Publisher
- Springer Netherlands
- Year
- 2011
- Tongue
- English
- Weight
- 312 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1573-9538
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## Abstract Brain and retinal capillary endothelial cells (BCECs and RCECs, respectively) exhibit a barrier structure and function. Comparison of gene expression in these cells could clarify the selective function of each barrier. The purpose of this study was to identify the genes selectively expr