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Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity

โœ Scribed by Cristalli, Gloria; Vittori, Sauro; Eleuteri, Alessandra; Grifantini, Mario; Volpini, Rosaria; Lupidi, Giulio; Capolongo, Laura; Pesenti, Enrico


Book ID
111859331
Publisher
American Chemical Society
Year
1991
Tongue
English
Weight
630 KB
Volume
34
Category
Article
ISSN
0022-2623

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Synthesis of 6-Substituted 1-Deazapurine
โœ Thomas Wenzel; Frank Seela ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 590 KB

## Abstract The synthesis of 6โ€substituted 1โ€deazapurine 2โ€ฒโ€deoxyribonucleosides is described. Glycosylation of the 1โ€deazapurine (imidazo[4,5โ€__b__]pyridine) anions with the ฮฑโ€Dโ€halogenose 5 gives stereoselectively __N__^7^โ€ and __N__^9^โ€ regioisomers. ^1^Hโ€NMR NOE and ^13^Cโ€NMR spectroscopy are u