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Purification of woodchuck hepatitis surface antigen using a monoclonal antibody raised against the antigen

✍ Scribed by Jennifer A Waters; Clare O'Neill; Ali Abdul-Gader; Robert Goldin; Peter Karayiannis; John Monjardino


Book ID
114139626
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
364 KB
Volume
93
Category
Article
ISSN
0166-0934

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The Fab fragment was cloned from the monoclonal cell line TAPC301-CL4, which was produced using the Epstein-Barr virus (EBV) transformation method. This cell line produces a human monoclonal antibody (CL4MAb) against the hepatitis B surface antigen (HBsAg). This MAb was shown to have hepatitis B vir