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Purification of VDAC (Voltage-dependent anion-selective channel) from rat liver mitochondria

✍ Scribed by Marco Colombini

Publisher: Springer
Year: 1983
Tongue: English
Weight: 663 KB
Volume: 74
Category: Article
ISSN: 0022-2631
DOI: 10.1007/bf01870500

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Voltage-dependent anion-selective channel proteins (VDACs) are pore-forming proteins found in the other mitochondrial membrane of all eukaryotes and in brain postsynaptic membranes. VDACs regulate anion fluxes of a series of metabolites including ATP, thus regulating mitochondrial metabolic function