Purification of the α-l-rhamnosidase of Penicillium decumbens and characterisation of two glycopeptide components

Synthesis of 1,5-dideoxy-1,5-imino-d-ara

Synthesis of 1,5-dideoxy-1,5-imino-d-arabinitol (5-nor-l-fuco-1-deoxynojirimycin) and its application for the affinity purification and characterisation of α-l-fucosidase

✍ Günter Legler; Arnold E. Stütz; Hermann Immich 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 871 KB

The title, 1,5-dideoxy-l,5-imino-D-arabinitol (2), was synthesized in seven steps from Darabinose with 5-azido-5-deoxy-o-arabinofuranose as key intermediate and 40% overall yield. An affinity procedure employing the N-carboxypentyl derivative of 2 linked to aminohexyl agarose permitted the isolation