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Purification of the membrane-form variant surface glycoprotein of Trypanosoma brucei

✍ Scribed by Dietmar Schell; Peter Overath

Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
347 KB
Volume
521
Category
Article
ISSN
1873-3778

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The production of the variant surface glycoprotein coat of bloodstream form African trypanosomes ceases after conversion to the procyclic form. In the bloodstream stage alternate expression of different variant surface glycoprotein genes is responsible for the antigenic variation that occurs during

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The variable surface glycoprotein (VSG) genes of Trypanosoma brucei have been classified into two groups depending upon whether or not duplication of the genes is observed when they are expressed. We report here the observation of duplication apparently linked to espression of the ILTaT 1.3 gene in