We have developed a novel glycosylation strategy which enabled a highly convergent assembly of a hexasaccharide derived from group B type I11 Streptococcus.
Purification of preparative quantities of group B Streptococcus type III oligosaccharides
β Scribed by Lawrence C. Paoletti; Kenneth D. Johnson
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 378 KB
- Volume
- 705
- Category
- Article
- ISSN
- 1873-3778
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## Abstract For Abstract see ChemInform Abstract in Full Text.
Syntheses of the propyl glycosides (1-3) of beta-D-Galp-(1----4)-beta-D-GlcpNAc, beta-D-Glcp-(1----6)-[beta-D-Galp-(1----4)]-beta-D-GlcpNAc, and beta-D-Galp-(1----4)-beta-D-Glcp-(1----6)-[beta-D-Galp-(1----)]-beta-D- GlcpNAc, respectively, are reported. Reaction of allyl 2-acetamido-3-O-benzyl-2-deo
A chemical synthesis of octasaccharide 1 is described in which (S)-l-carboxyethyl groups replace sialic acid residues to yield a mimic of two repeating units of the type III group B Streptococcus capsular polysaccharide.
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