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Purification of anti-histone-H1 antibodies and their use in measuring histone determinants in chromatin by radioimmunoadsorbance

✍ Scribed by Michael Bustin; Hanna Kupfer


Book ID
118311249
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
731 KB
Volume
68
Category
Article
ISSN
0006-291X

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The aim of this work was to study the accessibility of histone H1(0) and its structural domains to antibody binding in high molecular mass chromatin fragments of different conformations. Three types of specific antibody populations were used: (1) anti-H1(0) which reacted with antigenic determinants