Purification of a pluripotent neural stem cell from the adult mouse brain
β Scribed by Rietze, Rodney L.; Valcanis, Helen; Brooker, Gordon F.; Thomas, Tim; Voss, Anne K.; Bartlett, Perry F.
- Book ID
- 109775612
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 345 KB
- Volume
- 412
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/35089085
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## Abstract In the adult human brain, the presence of neural stem cells has been documented in the subgranular layer of the dentate gyrus of the hippocampus and in the subventricular zone of the lateral ventricles. Neurogenesis has also been reported in rodent models of ischemic stroke, traumatic b
## Background Down syndrome (DS), caused by trisomy of human chromosome 21 (HSA21), is the most common genetic cause of mental retardation in humans. Among complex phenotypes, it displays a number of neural pathologies including smaller brain size, reduced numbers of neurons, reduced dendritic spin