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Purification method development for chiral separation in supercritical fluid chromatography with the solubilities in supercritical fluid chromatographic mobile phases

✍ Scribed by Kyung H. Gahm; Helming Tan; Jodi Liu; Wesley Barnhart; John Eschelbach; Steve Notari; Samuel Thomas; David Semin; Janet Cheetham

Book ID
108189405
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
727 KB
Volume
46
Category
Article
ISSN
0731-7085

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## Abstract A strategy, including a rapid screening and several optimisation steps, for the separation of chiral molecules of pharmaceutical interest by polar organic solvent chromatography (POSC), using four polysaccharide‐based stationary phases, is proposed and compared with previously reported