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Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein

✍ Scribed by Carter, D. B.; Deibel, M. R.; Dunn, C. J.; Tomich, C.-S. C.; Laborde, A. L.; Slightom, J. L.; Berger, A. E.; Bienkowski, M. J.; Sun, F. F.; McEwan, R. N.

Book ID
109763215
Publisher
Nature Publishing Group
Year
1990
Tongue
English
Weight
898 KB
Volume
344
Category
Article
ISSN
0028-0836

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πŸ“œ SIMILAR VOLUMES

Purification, cloning, expression and bi
Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein
✍ Carter, D. B.; Deibel, M. R.; Dunn, C. J.; Tomich, C.-S. C.; Laborde, A. L.; Sli πŸ“‚ Article πŸ“… 1990 πŸ› Nature Publishing Group 🌐 English βš– 898 KB

A human myelomonocytic cell line, U937, produced an interleukin-1 (IL-1) receptor antagonist protein (IRAP) which was purified and partially sequenced. A complementary DNA coding for IRAP was cloned and sequenced. The mature translation product of the cDNA has been expressed in Escherichia coli and