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Purification and properties of two endonucleases specific for apurinic/apyrimidinic sites in DNA from Saccharomyces cerevisiae

✍ Scribed by Alexander T. Akhmedov; Oleg K. Kaboev; Michael L. Bekker

Book ID
119118932
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
547 KB
Volume
696
Category
Article
ISSN
0167-4781

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Endonuclease for apurinic sites in yeast
Endonuclease for apurinic sites in yeast comparison of the enzyme activity in the wild type and in rad mutants of Saccharomyces cerevisiae to MMS
✍ Chlebowicz, Ewa ;Jachymczyk, Witold J. πŸ“‚ Article πŸ“… 1977 πŸ› Springer 🌐 English βš– 223 KB

It was found that yeast cells contain an endonuclease specific for apurinic sites in DNA which has no effect on DNA with normal strands or on strands with alkylated sites. The enzyme activity was studied in the RAD strain and in rad 6, rad 18-2 and rad 21 mutants, all very sensitive to MMS, as compa