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Purification and Properties of a Nuclear Exoribonuclease from Ehrlich Ascites Tumor Cells

✍ Scribed by Harrison M. Lazarus and Michael B. Sporn

Book ID
123647784
Publisher
National Academy of Sciences
Year
1967
Tongue
English
Weight
997 KB
Volume
57
Category
Article
ISSN
0027-8424

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We have developed a simple and rapid method for isolation of purified nuclear lamina from Ehrlich ascites tumor cells. The procedure employs chromatin structures prepared from whole cells at low ionic strength and is carried out under conditions that minimize the formation of artifactual protein-DNA