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Purification and functional characterization of aquaporin-8

✍ Scribed by Kun Liu; Hiroaki Nagase; Chunyi George Huang; Giuseppe Calamita; Peter Agre

Book ID
119739516
Publisher
Portland Press
Year
2006
Tongue
English
Weight
557 KB
Volume
98
Category
Article
ISSN
0248-4900

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Expression and functional characterization of NPA motif-null aquaporin-1 mutations
✍ Yong Jiang πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 224 KB

## Abstract The asparagine‐proline‐alanine sequences (NPA motifs) in Loops B and E of aquaporin are highly conserved. To investigate the role of two NPA motifs in the structure and function of aquaporin water channels, we generated human aquaporins (AQP)‐1 mutations with NPA1 deletion, NPA2 deletio