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Purification and Cloning of Aggrecanase-1: A Member of the ADAMTS Family of Proteins

✍ Scribed by Tortorella, M. D.

Book ID
121161122
Publisher
American Association for the Advancement of Science
Year
1999
Tongue
English
Weight
428 KB
Volume
284
Category
Article
ISSN
0036-8075

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✍ Priya S. Chockalingam; Weilan Zeng; Elisabeth A. Morris; Carl R. Flannery πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 379 KB

## Abstract ## Objective To determine whether aggrecanase (ADAMTS) activities in articular cartilage can directly lead to the release of hyaluronan (HA) and hyaladherins (aggrecan G1 domain and link proteins), as may occur ex vivo during stimulation of cartilage explants with interleukin‐1 (IL‐1)