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Purification and characterization of T cell protein tyrosine phosphatase reveals significant functional homology to protein tyrosine phosphatase-1B

✍ Scribed by Yolanda Romsicki; Brian P. Kennedy; Ernest Asante-Appiah

Book ID
117042548
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
429 KB
Volume
414
Category
Article
ISSN
0003-9861

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PTP-MEG2 is an intracellular protein tyrosine phosphatase with a putative lipid-binding domain at the N-terminus. The present study reports expression, purification, and characterization of the full-length form of the enzyme plus a truncated form containing the catalytic domain alone. Full-length PT