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Purification and Characterization of Recombinant Rat Hepatic CYP4F1

✍ Scribed by Yasushi Kikuta; Emi Kusunose; Miyuki Ito; Masamichi Kusunose

Book ID
115567686
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
58 KB
Volume
369
Category
Article
ISSN
0003-9861

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## Abstract We report a comprehensive examination of rat hepatic CYP1A2 and CYP2E1 ontogeny. We compare the data to human data to determine the rat's capacity as a model to identify CYP‐mediated mechanisms underlying age‐dependent differences in susceptibility to toxicity. We evaluated CYP expressi