Purification and characterization of recombinant Caulobacter crescentus Cu,Zn superoxide dismutase
โ Scribed by Ivana De Domenico; Amalia Lania; Maria Carmela Bonaccorsi di Patti; Andrea Battistoni; Giovanni Musci; Alessandro Desideri
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 154 KB
- Volume
- 1764
- Category
- Article
- ISSN
- 1570-9639
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Prophylactic, intratracheal instillation of recombinant human Cu/Zn superoxide dismutase (rhSOD) has been shown to lessen lung injury produced by 48 h of hyperoxia and mechanical ventilation in neonatal piglets. However, instillation of small volumes of rhSOD intratracheally would not be expected to
## Abstract The inhibitory effect of recombinant human Cu^++^Zn^++^superoxide dismutase (rhSOD) on metastasis of tumor cells in the mouse was investigated. In an experimental pulmonary metastasis model employing Moth A cells as inoculum, significant inhibition of metastasis was obtained by intraven