Purification and characterization of protein methylase II from Helicobacter pylori
โ Scribed by Young Man Kim; Seong Hoon Ahn; Dong Wan Seo; Yong Kee Kim; Jeung Whan Han; Sungyoul Hong; Sangduk Kim; Woon Ki Paik; Hyang Woo Lee
- Book ID
- 109324799
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 223 KB
- Volume
- 195
- Category
- Article
- ISSN
- 0378-1097
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## Abstract Urease plays a central role in the pathogenesis of __Helicobacter pylori__ in humans. Maturation of this nickel metalloenzyme in bacteria requires the participation of the accessory proteins UreD (termed UreH in __H. pylori__), UreF, and UreG, which form sequential complexes with the ur
## Abstract Thymidylate synthase X (ThyX) catalyzes the methylation of dUMP to form dTMP in bacterial life cycle and is regarded as a promising target for antibiotics discovery. __Helicobacter pylori__ is a human pathogen associated with a number of human diseases. Here, we cloned and purified the