Purification and characterization of Helicobacter pylori arginase, RocF: unique features among the arginase superfamily

Insight into the role of a unique SSEHA

Insight into the role of a unique SSEHA motif in the activity and stability of Helicobacter pylori arginase

✍ Abhishek Srivastava; Nidhi Dwivedi; Uttamkumar Samanta; Apurba Kumar Sau 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 753 KB

## Abstract Arginase is a binuclear Mn^2+^‐metalloenzyme of urea cycle that hydrolyzes arginine to ornithine and urea. Unlike other arginases, the __Helicobacter pylori__ enzyme is selective for Co^2+^ and has all conserved motifs except ^88^SSEHA^92^ (instead of GGDHS). To examine the role of this