Secondary mouse embryo fibroblasts produce a growth inhibitor with the character of a thermolabile, nondialysable protein. The inhibitor was harvested from conditioned medium, and following G-75 Sephadex fractionation it was isolated in one peak which consisted of two fractions eluting at approximat
β¦ LIBER β¦
Purification and characterization of a DNA synthesis inhibitor protein from mouse embryo fibroblasts
β Scribed by S. Srinivas; T. Nagashunmugam; G. Shanmugam
- Book ID
- 112829060
- Publisher
- Indian Academy of Sciences
- Year
- 1991
- Tongue
- English
- Weight
- 481 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0250-5991
No coin nor oath required. For personal study only.
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## Abstract A number of bisdioxopiperazines have recently been shown to possess marked growthβinhibitory activity against a range of experimental tumours in mice and rats. These compounds were originally designed as potential intracellularly activated chelating agents. In the present investigation,