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Purification and characterization of a 26-kDa competitive inhibitor of interleukin 1

✍ Scribed by Gonzalo J. Mazzei; Philippe L. Seckinger; Jean-Michel Dayer; Alan R. Shaw


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
983 KB
Volume
20
Category
Article
ISSN
0014-2980

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## Abstract ## Objective To investigate whether the soluble form of interleukin‐1 (IL‐1) receptor accessory protein (sIL‐1RAcP), whose physiologic function remains to be established, can serve as a specific inhibitor of IL‐1 signaling in vitro, and to evaluate its applicability in collagen‐induced