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Purification and ATP Hydrolysis of the Putative Cholesterol Transporters ABCG5 and ABCG8 †

✍ Scribed by Wang, Zhanling; Stalcup, Lindsay D.; Harvey, Brandy J.; Weber, Joachim; Chloupkova, Maja; Dumont, Mark E.; Dean, Michael; Urbatsch, Ina L.

Book ID
126817784
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
390 KB
Volume
45
Category
Article
ISSN
0006-2960

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Phytosterolemia or Sitosterolemia is a rare autosomal recessive disorder characterized by highly elevated plasma levels of plant sterols and cholesterol as a consequence of hyperabsorption and impaired biliary secretion of sterols. The disease is caused by mutations in two half size ATP-binding cass