## Communicated by Ulf Landergren Subtelomeric rearrangements are an important cause of both isolated and familial idiopathic mental retardation. A variety of different rearrangements such as pure truncations, unbalanced translocations, interstitial deletions, and inverted duplications have been
β¦ LIBER β¦
Pure subtelomeric microduplications as a cause of mental retardation
β Scribed by EM Ruiter; DA Koolen; T Kleefstra; WM Nillesen; R Pfundt; N De Leeuw; BCJ Hamel; HG Brunner; EA Sistermans; BBA De Vries
- Book ID
- 110888469
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 331 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0009-9163
No coin nor oath required. For personal study only.
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In recent years, subtelomeric rearrangements, e.g., chromosome deletions or duplications too small to be detected by conventional cytogenetic analysis, have emerged as a significant cause of both idiopathic and familial mental retardation. As mental retardation is a common disorder, many patients ne