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Pure hair–nail ectodermal dysplasia maps to chromosome 12p11.1–q21.1 in a consanguineous Pakistani family

✍ Scribed by M. Naeem; P. John; G. Ali; W. Ahmad


Book ID
108694357
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
593 KB
Volume
32
Category
Article
ISSN
0307-6938

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Hidrotic ectodermal dysplasia (HED), Clouston syndrome (MIM No. 129500), is an autosomal dominant disorder affecting the skin and its derivatives. It is characterized by alopecia, dysplastic nails in hands and feet, and hyperkeratosis of the palms and soles. We have studied a large Indian pedigree (