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PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect

โœ Scribed by Tunaru, Sorin; Kero, Jukka; Schaub, Annette; Wufka, Christian; Blaukat, Andree; Pfeffer, Klaus; Offermanns, Stefan


Book ID
109933230
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
269 KB
Volume
9
Category
Article
ISSN
1078-8956

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PUMA-G and HM74 are receptors for nicoti
โœ Tunaru, Sorin; Kero, Jukka; Schaub, Annette; Wufka, Christian; Blaukat, Andree; ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 269 KB

Nicotinic acid (niacin), a vitamin of the B complex, has been used for almost 50 years as a lipid-lowering drug. The pharmacological effect of nicotinic acid requires doses that are much higher than those provided by a normal diet. Its primary action is to decrease lipolysis in adipose tissue by inh