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Pulsed Ultrafiltration Mass Spectrometry: A New Method for Screening Combinatorial Libraries

โœ Scribed by van Breemen, Richard B.; Huang, Chao-Ran; Nikolic, Dejan; Woodbury, Charles P.; Zhao, Yong-Zhong; Venton, Duane L.


Book ID
121208142
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
272 KB
Volume
69
Category
Article
ISSN
0003-2700

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## Abstract A new methodology for the rapid assessment of affinity ligands synthesized by combinatorial solidโ€phase chemistry is reported. This screening strategy utilizes the target protein conjugated to FITC, and represents an almost universal technique for the preliminary screening of solidโ€phas