Enhancement of phorbol ester-induced pro
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James C. Gay; Ella S. Stitt
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Article
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1988
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John Wiley and Sons
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English
⚖ 962 KB
We have shown that platelet-activating factor (PAF), a weak primary stimulus for neutrophil superoxide generation, synergistically enhances neutrophil oxidative responses to the tumor promoter phorbol myristate acetate (PMA). Since PMA is known to cause cytosol-to-membrane shift of calcium-activated