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Pulse sequence and parameter choice in NMR imaging as a problem of constrained multidimensional nonlinear optimization

✍ Scribed by Wolfgang Dreher; Peter Börnert


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
506 KB
Volume
8
Category
Article
ISSN
0740-3194

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✦ Synopsis


The advantage of the multiparametric nature of NMR imaging is connected with the problem of finding optimum pulse sequences and sequence parameters, which ensure a high contrast-to-noise ratio. For a given imaging task with m ( m > 2) regions characterized by sets of NMR parameters (e.g., p, T I , T,) two functions are proposed, which can be used to transform the search for an optimum pulse sequence into a problem of constrained multidimensional nonlinear optimization. The numerical algorithm is described and the results of two examples are presented and discussed. A short description of useful extensions of the proposed optimization approach, which are currently implemented, is given.