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Pulse Cyclophosphamide Therapy and Clinical Remission in Atypical Hemolytic Uremic Syndrome With Anti–Complement Factor H Autoantibodies

✍ Scribed by Olivia Boyer; Eve Balzamo; Marina Charbit; Nathalie Biebuyck-Gougé; Rémi Salomon; Marie-Agnès Dragon-Durey; Véronique Frémeaux-Bacchi; Patrick Niaudet


Book ID
114469527
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
371 KB
Volume
55
Category
Article
ISSN
0272-6386

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Many of the complement regulatory genes within the RCA cluster (1q32) have arisen through genomic duplication and the resulting high degree of sequence identity is likely to predispose to gene conversion events. The highest degree of identity is between the genes for factor H (CFH) and five factor H