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Pulmonary ventilation-perfusion MR imaging in clinical patients

✍ Scribed by Toshio Nakagawa; Hajime Sakuma; Shuichi Murashima; Nanaka Ishida; Kaname Matsumura; Kan Takeda


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
265 KB
Volume
14
Category
Article
ISSN
1053-1807

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✦ Synopsis


Abstract

The purpose of this study was to evaluate the feasibility of comprehensive magnetic resonance (MR) assessment of pulmonary perfusion and ventilation in patients. Both oxygen‐enhanced ventilation MR images and first‐pass contrast‐enhanced perfusion MR images were obtained in 16 patients with lung diseases, including pulmonary embolism, lung malignancy, and bulla. Inversion recovery single‐shot fast spin‐echo images were acquired before and after inhalation of 100% oxygen. The overall success rate of perfusion MR imaging and oxygen‐enhanced MR imaging was 94% and 80%, respectively. All patients with pulmonary embolism showed regional perfusion deficits without ventilation abnormality on ventilation‐perfusion MR imaging. The results of the current study indicate that ventilation‐perfusion MR imaging using oxygen inhalation and bolus injection of MR contrast medium is feasible for comprehensive assessment of pulmonary ventilation‐perfusion abnormalities in patients with lung diseases. J. Magn. Reson. Imaging 2001;14:419–424. © 2001 Wiley‐Liss, Inc.


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