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Pulmonary Hypertension

✍ Scribed by Alfred P. Fishman (auth.), Nicholas S. Hill MD, Harrison W. Farber MD (eds.)


Publisher
Humana Press
Year
2008
Tongue
English
Leaves
448
Series
Contemporary Cardiologyβ„’
Edition
1
Category
Library

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✦ Synopsis


This timely volume addresses the areas of pathophysiology and therapy of pulmonary hypertension, which have seen exciting developments over the past decade. The discoveries of endothelin overexpression as well as prostacyclin and nitric oxide deficiency in association with pulmonary hypertension have led to important therapeutic insights. In addition, the identification of genes associated with pulmonary hypertension has just begun to open the door to new pathophysiologic insights. The new therapies have led to significant improvements in patient function, quality of life and survival.

This book will be of interest not only to cardiologists, pulmonary specialists and rheumatologists, but also many nurses and pharmacotherapists are becoming increasingly involved in the therapy of patients with pulmonary hypertension.

✦ Table of Contents


Front Matter....Pages I-XV
Historical Perspective: A Century of Primary (Idiopathic) Pulmonary Hypertension....Pages 1-13
Classification of Pulmonary Hypertension....Pages 15-31
Diagnostic Approach to Pulmonary Arterial Hypertension....Pages 33-50
Pathophysiology of Pulmonary Arterial Hypertension....Pages 51-72
Pulmonary Hypertension Genes....Pages 73-92
The Right Ventricle in Pulmonary Hypertension....Pages 93-125
Congenital Heart Disease Associated with Pulmonary Arterial Hypertension....Pages 127-143
Connective Tissue Disease Associated Pulmonary Hypertension....Pages 145-171
Pulmonary Hypertension Associated with HIV, Liver Disease, Sarcoidosis, and Sickle Cell Disease....Pages 173-198
Chronic Thromboembolic Pulmonary Hypertension....Pages 199-230
General Therapeutic Approach and Traditional Therapies....Pages 231-253
Prostacyclin Therapy for Pulmonary Arterial Hypertension....Pages 255-281
Endothelin and Its Blockade in Pulmonary Arterial Hypertension....Pages 283-303
PDE5 Inhibitors and the cGMP Pathway in Pulmonary Arterial Hypertension....Pages 305-319
Statins for Treatment of Pulmonary Hypertension....Pages 321-336
Transitions and Combination Therapy for Pulmonary Arterial Hypertension....Pages 337-362
Acute Right Ventricular Dysfunction: Focus on Acute Cor Pulmonale....Pages 363-382
Lung Transplantation and Atrial Septostomy for Pulmonary Arterial Hypertension....Pages 383-403
New Directions in Pulmonary Hypertension Therapy....Pages 405-430
Back Matter....Pages 431-444

✦ Subjects


Cardiology; Pneumology/Respiratory System; Rheumatology; Angiology


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