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Pulmonary granulomata. A complication of intravesical administration of bacillus calmette-guerin for superficial bladder carcinoma

✍ Scribed by Robert L. Smith; Robert F. Alexander; Conrado P. Aranda

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 229 KB
Volume: 71
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19930301)71:5<1846::aid-cncr2820710521>3.0.co;2-o

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✦ Synopsis

Intravesical administration of bacillus Calmette-Guerin (BCG) is an effective treatment for superficial carcinoma of the bladder. The authors report a pulmonary complication characterized by miliary infiltration on chest roentgenogram and caseating granulomata on lung biopsy specimens. This case and three prior reports suggest that this complication may be a form of hypersensitivity rather than true BCG infection. Cancer 1993; 71:1846-7.

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