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Pulmonary Expression of Inducible Heme-Oxygenase after Ischemia/Reperfusion of the Lower Extremities in Rats

✍ Scribed by Cherif N. Boutros; Rachid Zegdi; Nermine Lila; Michele Combillau; Paul Fornes; Alain Carpentier; Jean Noel Fabiani


Book ID
116701928
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
426 KB
Volume
129
Category
Article
ISSN
0022-4804

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Heme oxygenase (HO) isozymes, HO-1 and HO-2 catalyze the cleavage of heme b to form the antioxidant biliverdin IXa, iron and the putative cellular messenger carbon monoxide (CO). Heat and stress have been reported to induce the expression of HO-1, in analogy to ubiquitin, a protein of 8 kDa involved