## Abstract ## BACKGROUND: Tamoxifen therapy is reported to increase the risk of deep venous thrombosis and pulmonary embolism (DVT/PE). To the authors' knowledge, it is not yet known whether the risk changes with the amount of time elapsed since the initial tamoxifen prescription. This informatio
β¦ LIBER β¦
Pulmonary embolism and cancer: Predisposition to venous thrombosis and embolism as a paraneoplastic syndrome
β Scribed by Hans U. Sons
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 854 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0022-4790
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β¦ Synopsis
In patients with a malignant primary disease the risk of thromboembolic complication is demonstrably increased. This is undoubtedly attributable to a whole range of factors (multifactorial etiology) which are highlighted in the present synoptic study. In addition to local influences from the tumor, a particular role appears to be played by an increased aggregation of thrombocytes, various tumor cell products, polyglobulism, hypercalcemia, increased release of thrombocinase, microthrombotic embolization, and a decrease in antithrombin 111.
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