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Pulmonary CD4+ cytokine responses in mice reveal differences in the relative immunogenicity of cold-adapted influenza A vaccine donor strains

โœ Scribed by Mark D. Wareing; Leonard C. Harrison; Gregory A. Tannock


Book ID
116957708
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
110 KB
Volume
23
Category
Article
ISSN
0264-410X

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## Abstract The immunogenicity of the Russian coldโ€adapted (ca) donor stains, A/Leningrad (Len)/134/17/57 and A/Leningrad/134/47/57, and the US strain A/Ann Arbor (AA)/6/60โ€ca, were compared in BALB/c mice with their respective wildโ€type parental viruses. Each ca donor strain was less immunogenic t